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Crohn's disease is a chronic disorder of the gastro intestinal tract, which is characterized by inflammation, and causes difficult digestion and general disability. Crohn’s is one of the very common irritable bowel syndromes / diseases (IBS/D) which affects several hundreds of individuals. In addition to Crohn’s disease, ulcerative colitis is another IBD which is common.
There have been some research studies in the recent past, which have indicated the potential benefits of the Human Growth Hormone Replacement Therapy, to treat patients with Crohn’s disease. A dietary modification which comprises of high protein diet and an adequate intake of folvite has been suggested, in addition to the hormone replacement therapy to effectively manage the condition.
Research indicating the role of the Human Growth Hormone in the management of Crohn’s Disease
A study was conducted on thirty seven adults suffering from moderate to severe form of active Crohn’s disease, by Dr. Alfred Slonim and his colleagues at the North Shore University Hospital in Manhasset, New York. The participants were administered 5 mg of HGH with a maintenance dose of 1.5 mg for a period of four months. Also, dietary modifications were suggested to the case and the control groups.
For a period of four months, the disease activity was evaluated using Crohn’s Disease Activity Index. It was observed that in patients treated with HGH, the improvement was about 100 %. Minor side effects were observed in the case group (i.e. participants treated with HGH) which included: edema and headache, which disappeared after the first month of the treatment. The study concluded that HGH has significant benefits in the management of patients suffering from Crohn’s Disease and it also aids in making the intestinal tissue healthier. The study was published in the New England Journal of Medicine in 2000. The study also observed that the benefit of Growth hormone was similar to the use of anti inflammatory drug infliximab (which is the only approved treatment for patients with Crohn’s disease).
HGH treats Crohn’s disease effectively
Crohn's Disease is manifested in the form of abdominal pain, diarrhea and bleeding, due to a breakdown of the intestinal wall. Unfortunately, neither the cause nor an approved treatment solution for the same is available. One of the reasons cited for the development of the condition is an exaggerated immune response which results in tissue damage.
There is little information about how HGH assists in the management of Crohn’s disease, nevertheless, a rational explanation is available. Firstly, HGH improves cell mediated response to antibodies and programs the immune system to respond by creating specific antigens. This is one of the reasons why HGH has been potentially beneficial in patients suffering from HIV AIDS or from autoimmune disorders like lupus and arthritis. Secondly, HGH promotes organ restoration and helps in the growth and proliferation of intestinal tissue, which in turn, improves the patient’s clinical condition.
The Human Growth Hormone is a potential solution for patients suffering from IBS including Crohn’s disease, especially, in conjunction with dietary and life style changes.