Human Growth Hormone

The Most Complete and Accurate Human Growth Hormone Guide in the World


Function Of HGH


Read the Following article on "Function Of HGH".
What Is The Function Of HGH?

Human growth hormone is an important hormone in the body. It is the hormone which is responsible for growth and development of cells and tissues of the body. It makes the body efficient in its function. HGH is produced by the pituitary gland. The ability of the pituitary gland to produce HGH declines very little with aging in most people. The decline with aging occurs one step back from the actual secretion of HGH by the pituitary.

Human growth hormone is now being produced artificially by the use or recombinant DNA technology. This is because many investigators have realized its good functions and benefits, and so they are finding ways on how to maximize production of this magnificent hormone.

However, what is specifically the function of human growth hormone?

Function of HGH

Human growth hormone is produced by the pituitary gland during childhood and puberty and this happens for a particular reason—to make us grow tall and big and to maximize the potential of our body organs. However, if we delve deeper it has a number of effects which is related to growth. The effects of growth hormone on the tissues of the body can generally be described as anabolic or building up. Like most other protein hormones, GH acts by interacting with a specific receptor on the surface of cells.

There are various ways on how human growth hormone affects the growth and regeneration of cells, particularly muscle cells. Because polypeptide hormones are not fat-soluble, they cannot penetrate sarcolemma. Thus, human growth hormone exerts some of its effects by binding to receptors on target cells, where it activates a second messenger. Through this mechanism GH directly stimulates division and multiplication of cells in the body.

Human growth hormone is also said to stimulate the production of insulin-like growth factor 1, a hormone similar to proinsulin. The liver is a major target organ for this process and is the principal site of IGF-1 production. IGF-1 has growth-stimulating effects on a wide variety of tissues.

Altogether, these two mechanisms by which human growth hormone takes effect create growth and development of body cells, tissue and organs. Furthermore, it also increases calcium retention, and strengthens and increases the mineralization of bone. It increases muscle mass through sarcomere hyperplasia. It also promotes lipolysis or burning of fat leading to weight loss and more energy; it increases protein synthesis, stimulates the growth of all internal organs excluding the brain, plays a role in fuel homeostasis, reduces liver uptake of glucose, promotes gluconeogenesis in the liver, contributes to the maintenance and function of pancreatic islets and stimulates the immune system to fight against infections.